Please note that this price excludes VAT and 20% VAT will be added at checkout. If you suffer from a chronic illness, you can claim back the VAT at checkout FRÍO® keeps temperature sensitive medicines within safe temperatures of 18-26°C (64.4-78.8°F) for a minimum of 45 hours, even in a constant environmental temperature of 37.8°C (100°F). - Keeps in-use insulin and temperature sensitive medication cool and safe - Simply activate with cold water - Light and compact - Reusable There is a seperate inside zip on the Medication Purse to keep personal belongings such as Bank Cards and Mobile Phone. Suitable for carrying a range of medication and cosmetics. Will hold up to 3 insulin pens, or 1 pen and 4 cartridges. Note: we recommend that a waterproof liner is used with metal pens or with any electronic timing device or any accessory with electronic components to protect it from moisture.